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1

TALE nucleases: tailored genome engineering made easy

Claudio Mussolino, Toni Cathomen

Journal:

Current Opinion in Biotechnology

Year:

2012

Language:

english

File:

PDF, 721 KB

english, 2012

2

RNA guides genome engineering

Mussolino, Claudio, Cathomen, Toni

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 298 KB

english, 2013

3

Inactivation of Hepatitis B Virus Replication in Cultured Cells and In Vivo with Engineered Transcription Activator-Like Effector Nucleases

Bloom, Kristie, Ely, Abdullah, Mussolino, Claudio, Cathomen, Toni, Arbuthnot, Patrick

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 2.69 MB

english, 2013

4

Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute

Lee, Seung Hwan, Turchiano, Giandomenico, Ata, Hirotaka, Nowsheen, Somaira, Romito, Marianna, Lou, Zhenkun, Ryu, Seuk-Min, Ekker, Stephen C, Cathomen, Toni, Kim, Jin-Soo

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 132 KB

english, 2016

5

Refining strategies to translate genome editing to the clinic

Cornu, Tatjana I, Mussolino, Claudio, Cathomen, Toni

Journal:

Nature Medicine

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

6

MicroRNA-221 regulates FAS-induced fulminant liver failure

Amar Deep Sharma, Nidhi Narain, Eva-Maria Händel, Marcus Iken, Nishant Singhal, Toni Cathomen, Michael P. Manns, Hans R. Schöler, Michael Ott, Tobias Cantz

Journal:

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

7

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

Szczepek, Michal, Brondani, Vincent, Büchel, Janine, Serrano, Luis, Segal, David J, Cathomen, Toni

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 453 KB

english, 2007

8

Reply to “Genome editing with modularly assembled zinc-finger nucleases”

Joung, J Keith, Voytas, Daniel F, Cathomen, Toni

Journal:

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

9

A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain

Cathomen, Toni, Mrkic, Branka, Spehner, Danièle, Drillien, Robert, Naef, Roland, Pavlovic, Jovan, Aguzzi, Adriano, Billeter, Martin A., Cattaneo, Roberto

Journal:

The EMBO Journal

Year:

1998

Language:

english

File:

PDF, 901 KB

english, 1998

10

Preferential Initiation at the Second AUG of the Measles Virus F mRNA: A Role for the Long Untranslated Region

TONI CATHOMEN, CHRISTIAN J. BUCHHOLZ, PIUS SPIELHOFER, ROBERTO CATTANEO

Journal:

Year:

1995

Language:

english

File:

PDF, 135 KB

english, 1995

11

Selective Expression of a Subset of Measles Virus Receptor-Competent CD46 Isoforms in Human Brain

CHRISTIAN J. BUCHHOLZ, DENIS GERLIER, AIZHONG HU, TONI CATHOMEN, M.KATHRYN LISZEWSKI, JOHN P. ATKINSON, ROBERTO CATTANEO

Journal:

Year:

1996

Language:

english

File:

PDF, 118 KB

english, 1996

12

Highly Efficient Zinc-Finger Nuclease-Mediated Disruption of an eGFP Transgene in Keratinocyte Stem Cells without Impairment of Stem Cell Properties

Thorsten Höher, Lee Wallace, Kafaitullah Khan, Toni Cathomen, Julia Reichelt

Journal:

Stem Cell Reviews and Reports

Year:

2012

Language:

english

File:

PDF, 533 KB

english, 2012

13

Factors involved in measles virus budding

Danièle Spehner, Toni Cathomen, Séverine Vincent, Roberto Cattaneo, Denis Gerlier, Robert Drillien

Journal:

Biology of the Cell

Year:

1998

Language:

english

File:

PDF, 255 KB

english, 1998

14

Targeted genome editing in pluripotent stem cells using zinc-finger nucleases

Sylwia Bobis-Wozowicz, Anna Osiak, Shamim H. Rahman, Toni Cathomen

Journal:

Year:

2011

Language:

english

File:

PDF, 481 KB

english, 2011

15

MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration

Yuan, Qinggong, Loya, Komal, Rani, Bhavna, Möbus, Selina, Balakrishnan, Asha, Lamle, Jutta, Cathomen, Toni, Vogel, Arndt, Manns, Michael P., Ott, Michael, Cantz, Tobias, Sharma, Amar Deep

Journal:

Year:

2013

Language:

english

File:

PDF, 6.85 MB

english, 2013

16

Ultramicroscopy Reveals Axonal Transport Impairments in Cortical Motor Neurons at Prion Disease

Ermolayev, Vladimir, Friedrich, Mike, Nozadze, Revaz, Cathomen, Toni, Klein, Michael A., Harms, Gregory S., Flechsig, Eckhard

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 1.67 MB

english, 2009

17

Retargeting Sleeping Beauty Transposon Insertions by Engineered Zinc Finger DNA-binding Domains

Voigt, Katrin, Gogol-Döring, Andreas, Miskey, Csaba, Chen, Wei, Cathomen, Toni, Izsvák, Zsuzsanna, Ivics, Zoltán

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 850 KB

english, 2012

18

The Nontoxic Cell Cycle Modulator Indirubin Augments Transduction of Adeno-Associated Viral Vectors and Zinc-Finger Nuclease-Mediated Gene Targeting

Rahman, Shamim H., Bobis-Wozowicz, Sylwia, Chatterjee, Debanjana, Gellhaus, Katharina, Pars, Kaweh, Heilbronn, Regine, Jacobs, Roland, Cathomen, Toni

Journal:

Human Gene Therapy

Year:

2013

Language:

english

File:

PDF, 539 KB

english, 2013

19

Zinc-finger Nucleases: The Next Generation Emerges

Cathomen, Toni, Keith Joung, J

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

20

Efficient Designer Nuclease-Based Homologous Recombination Enables Direct PCR Screening for Footprintless Targeted Human Pluripotent Stem Cells

Merkert, Sylvia, Wunderlich, Stephanie, Bednarski, Christien, Beier, Jennifer, Haase, Alexandra, Dreyer, Anne-Kathrin, Schwanke, Kristin, Meyer, Johann, Göhring, Gudrun, Cathomen, Toni, Martin, Ulrich

Journal:

Stem Cell Reports

Year:

2014

Language:

english

File:

PDF, 2.01 MB

english, 2014

21

Construction and characterization of adenoviral vectors for the delivery of TALENs into human cells

Holkers, Maarten, Cathomen, Toni, Gonçalves, Manuel A.F.V.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

22

Interaction of Measles Virus Glycoproteins with the Surface of Uninfected Peripheral Blood Lymphocytes Induces Immunosuppression in vitro

Jorg Schlender, Jens-Jorg Schnorr, Pius Spielhofer, Toni Cathomen, Roberto Cattaneo, Martin A. Billeter, Volker Ter Meulen and Sibylle Schneider-Schaulies

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.50 MB

english, 1996

23

Translating the Genomic Revolution — Targeted Genome Editing in Primates

Phimister, Elizabeth G., Cathomen, Toni, Ehl, Stephan

Journal:

New England Journal of Medicine

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

24

Fate of Recombinant Adeno-Associated Viral Vector Genomes During DNA Double-Strand Break-Induced Gene Targeting in Human Cells

Gellhaus, Katharina, Cornu, Tatjana I., Heilbronn, Regine, Cathomen, Toni

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 2.76 MB

english, 2010

25

On target? Tracing zinc-finger-nuclease specificity

Mussolino, Claudio, Cathomen, Toni

Journal:

Year:

2011

Language:

english

File:

PDF, 733 KB

english, 2011

26

Adenoviral vector DNA for accurate genome editing with engineered nucleases

Holkers, Maarten, Maggio, Ignazio, Henriques, Sara F D, Janssen, Josephine M, Cathomen, Toni, Gonçalves, Manuel A F V

Journal:

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

27

Adding Fingers to an Engineered Zinc Finger Nuclease Can Reduce Activity

Shimizu, Yuka, Şöllü, Cem, Meckler, Joshua F., Adriaenssens, Alice, Zykovich, Artem, Cathomen, Toni, Segal, David J.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.87 MB

english, 2011

28

Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier

Rahman, Shamim H., Maeder, Morgan L., Joung, J. Keith, Cathomen, Toni

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

29

Versatile and Efficient Genome Editing in Human Cells by Combining Zinc-Finger Nucleases With Adeno-Associated Viral Vectors

Händel, Eva-Maria, Gellhaus, Katharina, Khan, Kafaitullah, Bednarski, Christien, Cornu, Tatjana I., Müller-Lerch, Felix, Kotin, Robert M., Heilbronn, Regine, Cathomen, Toni

Journal:

Human Gene Therapy

Year:

2012

Language:

english

File:

PDF, 374 KB

english, 2012

30

Generation and genetic modification of induced pluripotent stem cells

Schambach, Axel, Cantz, Tobias, Baum, Christopher, Cathomen, Toni

Journal:

Expert Opinion on Biological Therapy

Year:

2010

Language:

english

File:

PDF, 526 KB

english, 2010

31

Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery

Bobis-Wozowicz, Sylwia, Galla, Melanie, Alzubi, Jamal, Kuehle, Johannes, Baum, Christopher, Schambach, Axel, Cathomen, Toni

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 865 KB

english, 2014

32

Maßgeschneidertes Genom — Designer-Nukleasen im Einsatz

Bednarski, Christien, Cathomen, Toni

Journal:

Year:

2015

Language:

german

File:

PDF, 374 KB

german, 2015

33

Genome Editing Technologies: Defining a Path to Clinic

Corrigan-Curay, Jacqueline, O'Reilly, Marina, Kohn, Donald B, Cannon, Paula M, Bao, Gang, Bushman, Frederic D, Carroll, Dana, Cathomen, Toni, Joung, J Keith, Roth, David, Sadelain, Michel, Scharenberg

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 636 KB

english, 2015

34

Expanding or Restricting the Target Site Repertoire of Zinc-finger Nucleases: The Inter-domain Linker as a Major Determinant of Target Site Selectivity

Händel, Eva-Maria, Alwin, Stephen, Cathomen, Toni

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 986 KB

english, 2009

35

Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease

Ermolayev, Vladimir, Cathomen, Toni, Merk, Julia, Friedrich, Mike, Härtig, Wolfgang, Harms, Gregory S., Klein, Michael A., Flechsig, Eckhard, Agrimi, Umberto

Journal:

Year:

2009

Language:

english

File:

PDF, 735 KB

english, 2009

36

Integration Preferences of Wildtype AAV-2 for Consensus Rep-Binding Sites at Numerous Loci in the Human Genome

Hüser, Daniela, Gogol-Döring, Andreas, Lutter, Timo, Weger, Stefan, Winter, Kerstin, Hammer, Eva-Maria, Cathomen, Toni, Reinert, Knut, Heilbronn, Regine, Cullen, Bryan R.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.74 MB

english, 2010

37

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

Mock, Ulrike, Riecken, Kristoffer, Berdien, Belinda, Qasim, Waseem, Chan, Emma, Cathomen, Toni, Fehse, Boris

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

38

Targeted Genome Modifications Using Integrase‐deficient Lentiviral Vectors

Cornu, Tatjana I, Cathomen, Toni

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

39

Zinc-finger Nuclease-induced Gene Repair With Oligodeoxynucleotides: Wanted and Unwanted Target Locus Modifications

Radecke, Sarah, Radecke, Frank, Cathomen, Toni, Schwarz, Klaus

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 433 KB

english, 2010

40

DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases

Cornu, Tatjana I, Thibodeau-Beganny, Stacey, Guhl, Eva, Alwin, Stephen, Eichtinger, Magdalena, Joung, JK, Cathomen, Toni

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 270 KB

english, 2008

41

Histone Deacetylase Inhibition Rescues Gene Knockout Levels Achieved with Integrase-Defective Lentiviral Vectors Encoding Zinc-Finger Nucleases

Pelascini, Laetitia P.L., Maggio, Ignazio, Liu, Jin, Holkers, Maarten, Cathomen, Toni, Gonçalves, Manuel A.F.V.

Journal:

Human Gene Therapy Methods

Year:

2013

Language:

english

File:

PDF, 1.36 MB

english, 2013

42

Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome

Müller, Maximilian, Lee, Ciaran M., Gasiunas, Giedrius, Davis, Timothy H., Cradick, Thomas J., Siksnys, Virginijus, Bao, Gang, Cathomen, Toni, Mussolino, Claudio

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

43

[Advances in Experimental Medicine and Biology] Genome Editing ||

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 6.55 MB

english, 2016

44

[Advances in Experimental Medicine and Biology] Genome Editing || Strategies to Determine Off-Target Effects of Engineered Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 886 KB

english, 2016

45

[Advances in Experimental Medicine and Biology] Genome Editing || Engineered Nucleases and Trinucleotide Repeat Diseases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 445 KB

english, 2016

46

[Advances in Experimental Medicine and Biology] Genome Editing || The Development and Use of Zinc-Finger Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 309 KB

english, 2016

47

[Advances in Experimental Medicine and Biology] Genome Editing || Gene Editing 20 Years Later

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 295 KB

english, 2016

48

[Advances in Experimental Medicine and Biology] Genome Editing || Phage Integrases for Genome Editing

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 339 KB

english, 2016

49

[Advances in Experimental Medicine and Biology] Genome Editing || Using Engineered Nucleases to Create HIV-Resistant Cells

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 625 KB

english, 2016

50

[Advances in Experimental Medicine and Biology] Genome Editing || Cellular Engineering and Disease Modeling with Gene-Editing Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 752 KB

english, 2016

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